Abstract Library

#2815 Unexpected High Rate of Metastases in Type 1 Gastric Neuroendocrine Neoplasia

Introduction: Gastric neuroendocrine neoplasms (gNEN) represent about 7.5% of gastroenteropancreatic NEN (gepNEN), classified in: type 1 (70-80%), related to autoimmune gastritis, type 2 (5%), related to Zollinger-Ellison syndrome in multiple endocrine neoplasia 1 and type 3 (15-20%), in absence of hypergastrinemia or mucosal atrophy.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Bottiglieri F, Modica R, de Cicco F, Minotta R, Faggiano A,

Keywords: gastric, neuroendocrine, type1, type3, metastases,

#1756 Somatostatin Analogs in Patients with Multiple Endocrine Neoplasia Type 1 and Zollinger-Ellison Syndrome: Efficacy and Safety

Introduction: Zollinger-Ellison syndrome (ZES) can cause severe complications. In multiple endocrine neoplasia type 1 (MEN1) related ZES, surgery has a controversial role and proton pump inhibitors (PPI) are usually first-line therapy, although some concerns regarding long-term use. Somatostatin analogs (SSA) both reduce hypergastrinemia and have an antiproliferative role.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Modica R

Authors: Modica R, Pizza G, Lo Calzo F, De Cicco F, Sciammarella C,

Keywords: somatostatin analogs, MEN1, Zollinger-Ellison syndrome,

#1509 MEN1 Syndrome with Pancreatic Involvement and Synchronous Lung Adenocarcinoma: A Case Report

Introduction: Lung lesions in MEN1 patients makes us consider firstly a neuroendocrine tumor (NET) as carcinoids are part of MEN1 syndrome.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Liço V, Milanetto A, Alaggio R, Pedrazzoli S, Pasquali C,

Keywords: men1,

#1069 Gastric Neuroendocrine Neoplasms and Long-Term Proton Pump Inhibitors: Need for a Revision of Classifications?

Introduction: Gastric neuroendocrine neoplasm (gNENs) include three types: type 1 and 2 related to hypergastrinemia due to chronic atrophic gastritis(CAG) or Zollinger-Ellison syndrome (ZES) respectively, and type 3 normogastrinemic and more aggressive. Few cases of gNENs in patients taking proton pump inhibitors (PPI) have been reported

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Cavalcoli f

Authors: Cavalcoli F, Zilli A, Conte D, Ciafardini C, Massironi S,

Keywords: PPI, gNEN, classification, CAG,

#848 Zollinger-Ellison Syndrome: The Esophageal Stricture as a Rare and Severe Complication

Introduction: Zollinger-Ellison Syndrome (ZES) is caused by tumoral hypersecretion of gastrin, inducing gastric hyperchlorhydria and complicated peptic ulcer disease. Esophageal strictures are rare in ZES, due to early PPI treatment.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Liço V, Milanetto A, Moletta L, Vincenzi V, Ruol A,

Keywords: esophageal stricture, ZES, hypergastrinemia,